Review



sonic hedgehog  (R&D Systems)


Bioz Verified Symbol R&D Systems is a verified supplier
Bioz Manufacturer Symbol R&D Systems manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    R&D Systems sonic hedgehog
    Sonic Hedgehog, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 55 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+shh+protein/Recombinant+Mouse+Sonic+Hedgehog%2FShh%2C+N-Terminus+Protein/pm41747005-269-24-31
    Average 94 stars, based on 55 article reviews
    sonic hedgehog - by Bioz Stars, 2026-09
    94/100 stars

    Images

    Related Articles

    Activation Assay:

    Article Title: Immature mDA neurons ameliorate motor deficits in a 6-OHDA Parkinson's disease mouse model and are functional after cryopreservation.
    Article Snippet: Briefly, on day −1 of differentiation, iPS cells were plated onto Matrigel (BD Biosciences, 354230) at a density of 180,000 cells/cm2 in the presence of 100 nM LDN193189 (Stemgent, 04–0074) and 10 μM SB431542 (Stemgent, 01–0010–50) for dual SMAD inhibition. .. This was followed by activation of the sonic hedgehog pathway with 100 ng/ml recombinant SHH protein (R&D Systems, 464-SH) and 2 μM purmorphamine (Calbiochem, 540220). .. After floor plate induction, cells were differentiated in the presence of 20 ng/ml BDNF (R&D Systems, 248-BD), 0.2mM ascorbate (Sigma, A4034), 20 ng/ml GDNF (R&D Systems, 212-GD), 1 ng/ ml TGF-β3 (R&D Systems, 243-B3-10), 0.5 mM dibutryl-cAMP (Sigma, D0627), and 10 μM DAPT (Tocris, 2634).

    Article Title: KEAP1‐NRF2/HO‐1 Pathway Promotes Ferroptosis and Neuronal Injury in Schizophrenia
    Article Snippet: This was achieved by treating the cells with Noggin (Sino Biological, Cat. #10267‐HNAH) and SB431542 (Tocris, Cat. #1614) to block the TGF‐β and BMP signaling pathways. .. The NPCs were then directed toward medial ganglionic eminence (MGE)‐like progenitors through modulation of the sonic hedgehog (SHH) signaling using recombinant SHH protein (R&D Systems, Cat. #1845‐SH‐025) and activation of the WNT pathway with CHIR99021 (Stem cells, Cat. #99021). ..

    Article Title: KEAP1-NRF2/HO-1 Pathway Promotes Ferroptosis and Neuronal Injury in Schizophrenia.
    Article Snippet: This was achieved by treating the cells with Noggin (Sino Bio- logical, Cat. #10267-HNAH) and SB431542 (Tocris, Cat. #1614) to block the TGF-β and BMP signaling pathways. .. The NPCs were then directed toward medial ganglionic eminence (MGE)like progenitors through modulation of the sonic hedgehog (SHH) signaling using recombinant SHH protein (R&D Systems, Cat. #1845-SH-025) and activation of the WNT pathway with CHIR99021 (Stem cells, Cat. #99021). ..

    Recombinant:

    Article Title: Immature mDA neurons ameliorate motor deficits in a 6-OHDA Parkinson's disease mouse model and are functional after cryopreservation.
    Article Snippet: Briefly, on day −1 of differentiation, iPS cells were plated onto Matrigel (BD Biosciences, 354230) at a density of 180,000 cells/cm2 in the presence of 100 nM LDN193189 (Stemgent, 04–0074) and 10 μM SB431542 (Stemgent, 01–0010–50) for dual SMAD inhibition. .. This was followed by activation of the sonic hedgehog pathway with 100 ng/ml recombinant SHH protein (R&D Systems, 464-SH) and 2 μM purmorphamine (Calbiochem, 540220). .. After floor plate induction, cells were differentiated in the presence of 20 ng/ml BDNF (R&D Systems, 248-BD), 0.2mM ascorbate (Sigma, A4034), 20 ng/ml GDNF (R&D Systems, 212-GD), 1 ng/ ml TGF-β3 (R&D Systems, 243-B3-10), 0.5 mM dibutryl-cAMP (Sigma, D0627), and 10 μM DAPT (Tocris, 2634).

    Article Title: PM2.5 promotes human bronchial smooth muscle cell migration via the sonic hedgehog signaling pathway
    Article Snippet: .. In some experiments, 100 ng/ml recombinant Shh protein (r-Shh; R&D Systems, Minneapolis, MN, USA) was added to the lower chamber. .. In experiments where the SMO inhibitor, cyclopamine (Sigma-Aldrich, St. Louis, MO, USA), was used, cells were pretreated with the drug for 30 min prior to PM2.5 or r-Shh exposure.

    Article Title: KEAP1‐NRF2/HO‐1 Pathway Promotes Ferroptosis and Neuronal Injury in Schizophrenia
    Article Snippet: This was achieved by treating the cells with Noggin (Sino Biological, Cat. #10267‐HNAH) and SB431542 (Tocris, Cat. #1614) to block the TGF‐β and BMP signaling pathways. .. The NPCs were then directed toward medial ganglionic eminence (MGE)‐like progenitors through modulation of the sonic hedgehog (SHH) signaling using recombinant SHH protein (R&D Systems, Cat. #1845‐SH‐025) and activation of the WNT pathway with CHIR99021 (Stem cells, Cat. #99021). ..

    Article Title: Pervasive translational regulation of the cell signalling circuitry underlies mammalian development
    Article Snippet: On day 3, the media was supplemented with 30 nM Retinoic Acid (R2625-100MG, Sigma). .. After 8 h of culture, fresh media containing 30 nM RA and either 500 nM SAG (5666601-1 mg, Millipore/Calbiochem) or 2 μg ml −1 of recombinant SHH protein (464-SH-025, R&D) was added - this was counted as day 3.5. ..

    Article Title: Sonic hedgehog connects podocyte injury to mesangial activation and glomerulosclerosis
    Article Snippet: .. Isolated glomeruli were cultured in RPMI1640/10% FBS medium at 37°C on noncoated 6-well plates in the absence or presence of recombinant Shh protein (1324-WN-010; R&D Systems) for further analyses. ..

    Article Title: Sonic hedgehog connects podocyte injury to mesangial activation and glomerulosclerosis.
    Article Snippet: .. Isolated glomeruli were cultured in RPMI1640/10% FBS medium at 37°C on noncoated 6-well plates in the absence or presence of recombinant Shh protein (1324-WN-010; R&D Systems) for further analyses. ..

    Article Title: KEAP1-NRF2/HO-1 Pathway Promotes Ferroptosis and Neuronal Injury in Schizophrenia.
    Article Snippet: This was achieved by treating the cells with Noggin (Sino Bio- logical, Cat. #10267-HNAH) and SB431542 (Tocris, Cat. #1614) to block the TGF-β and BMP signaling pathways. .. The NPCs were then directed toward medial ganglionic eminence (MGE)like progenitors through modulation of the sonic hedgehog (SHH) signaling using recombinant SHH protein (R&D Systems, Cat. #1845-SH-025) and activation of the WNT pathway with CHIR99021 (Stem cells, Cat. #99021). ..

    Isolation:

    Article Title: Sonic hedgehog connects podocyte injury to mesangial activation and glomerulosclerosis
    Article Snippet: .. Isolated glomeruli were cultured in RPMI1640/10% FBS medium at 37°C on noncoated 6-well plates in the absence or presence of recombinant Shh protein (1324-WN-010; R&D Systems) for further analyses. ..

    Article Title: Sonic hedgehog connects podocyte injury to mesangial activation and glomerulosclerosis.
    Article Snippet: .. Isolated glomeruli were cultured in RPMI1640/10% FBS medium at 37°C on noncoated 6-well plates in the absence or presence of recombinant Shh protein (1324-WN-010; R&D Systems) for further analyses. ..

    Cell Culture:

    Article Title: Sonic hedgehog connects podocyte injury to mesangial activation and glomerulosclerosis
    Article Snippet: .. Isolated glomeruli were cultured in RPMI1640/10% FBS medium at 37°C on noncoated 6-well plates in the absence or presence of recombinant Shh protein (1324-WN-010; R&D Systems) for further analyses. ..

    Article Title: Sonic hedgehog connects podocyte injury to mesangial activation and glomerulosclerosis.
    Article Snippet: .. Isolated glomeruli were cultured in RPMI1640/10% FBS medium at 37°C on noncoated 6-well plates in the absence or presence of recombinant Shh protein (1324-WN-010; R&D Systems) for further analyses. ..



    Similar Products

    94
    R&D Systems sonic hedgehog
    Sonic Hedgehog, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+shh+protein/Recombinant+Mouse+Sonic+Hedgehog%2FShh%2C+N-Terminus+Protein/pm41747005-269-24-31
    Average 94 stars, based on 1 article reviews
    sonic hedgehog - by Bioz Stars, 2026-09
    94/100 stars
      Buy from Supplier

    94
    R&D Systems recombinant mouse shh n terminal protein
    Recombinant Mouse Shh N Terminal Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+shh+protein/Recombinant+Mouse+Sonic+Hedgehog%2FShh%2C+N-Terminus+Protein/pmc13041449-45-20-26
    Average 94 stars, based on 1 article reviews
    recombinant mouse shh n terminal protein - by Bioz Stars, 2026-09
    94/100 stars
      Buy from Supplier

    95
    R&D Systems shh
    Shh, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+shh+protein/Recombinant+Human+Sonic+Hedgehog%2FShh+Protein%2C+High+Activity/bio_rxiv__64898__2026__02__20__707051-217-14-15
    Average 95 stars, based on 1 article reviews
    shh - by Bioz Stars, 2026-09
    95/100 stars
      Buy from Supplier

    94
    R&D Systems e coli
    E Coli, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+shh+protein/Recombinant+Human+Sonic+Hedgehog%2FShh%2C+N-Terminus+Protein/bio_rxiv__64898__2026__02__23__707386-23-24-32
    Average 94 stars, based on 1 article reviews
    e coli - by Bioz Stars, 2026-09
    94/100 stars
      Buy from Supplier

    95
    R&D Systems hek cells
    Hek Cells, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+shh+protein/Recombinant+Human+Sonic+Hedgehog%2FShh+Protein%2C+High+Activity/bio_rxiv__64898__2026__02__23__707386-23-13-32
    Average 95 stars, based on 1 article reviews
    hek cells - by Bioz Stars, 2026-09
    95/100 stars
      Buy from Supplier

    95
    R&D Systems human shh
    Human Shh, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+shh+protein/Recombinant+Human+Sonic+Hedgehog%2FShh+Protein%2C+High+Activity/pm41507312-328-2-4
    Average 95 stars, based on 1 article reviews
    human shh - by Bioz Stars, 2026-09
    95/100 stars
      Buy from Supplier

    Image Search Results